chemotaxis and adherence Leukotriene B 4 is a potent and stereospecific stimulator of neutrophil
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منابع مشابه
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence.
We studied the effects of leukotrienes on in vitro functions of neutrophil polymorphonuclear (PMN) granulocytes. Leukotriene B4 (LTB4) evoked a stimulated and directed migration of neutrophils under agarose with an optimum concentration of 10(-6)M, whereas two nonenzymatically formed isomers (compounds I and II) induced this response at 10(-5)M. Leukotriene C4 (LTC4) and 5-hydroxyeicosate-traen...
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A sensitive gas chromatography-mass spectrometric method was used to measure the generation in whole blood of leukotriene B4 (LTB4), a potent stimulator of neutrophil chemotaxis, in eight patients with chronic granulocytic leukaemia (CGL) and 12 healthy controls. LTB4 was detectable in unstimulated samples from all the patients (mean 194 (70 SEM) pg/ml), and the capacity for LTB4 production aft...
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Leukotriene B4 (LTB4) is a potent primary stimulator of neutrophil chemotaxis, aggregation. and degranulation and induces superoxide production at higher concentrations. In order to determine whether LTB4 modulates neutrophil responses to oxidative stimuli, human neutrophils (PMNs) were incubated with LTB4 prior to stimulation with fMet-Leu-Phe (fMLP. 1 0 mol/L). opsonized zymosan (OZ. 250 tg/m...
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Leukotriene B4 (LTB4) is a potent primary stimulator of neutrophil chemotaxis, aggregation. and degranulation and induces superoxide production at higher concentrations. In order to determine whether LTB4 modulates neutrophil responses to oxidative stimuli, human neutrophils (PMNs) were incubated with LTB4 prior to stimulation with fMet-Leu-Phe (fMLP. 1 0 mol/L). opsonized zymosan (OZ. 250 tg/m...
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